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KMID : 0363320000210050819
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Journal of Korean Oriental Internal Medicine
2000 Volume.21 No. 5 p.819 ~ p.827
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The Effects of Hyulbuchukotang (HCE) on the Thrombosis Related Factors
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Kim Young-Sun
Park Jong-Hyung
Han Yang-Hee
Jeon Chan-Yong
Kim Dong-Woo
Park Se-Ki
Lee Chung-Jung-Hye
Go Seung-Hee
Go Jae-Chul
Choi You-Kyung
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Abstract
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Purpose : To investigate the inhibitory effect of HCE on platelet aggragation and erythrocyte deformiability, we performed following experiments.
Methods : Concentrated Hyulbuchukotang (HCE) was fed to rats for 10days. We compare normal group with 500β∑/β∑- high dose group and 100β∑/β -low dose group.
Results : HCE enhanced the blood filtration rate, erythrocyte deformiability, reduced the platelet aggreablilty and inhibited granule release from collagen stimulated platelet, the prostaglandin synthesis in platelat.
Conclusion : HCE should inhibit thrombos formation due to platelet hyperaggraeability and reduction of erythrocyte defonmiability.
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KEYWORD
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HCE, thrombos, platelet aggreability, erythrocyte deformiability
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